Source code for mordred.Autocorrelation

import numpy as np

from ._base import Descriptor
from ._graph_matrix import DistanceMatrix
from ._atomic_property import AtomicProperty, get_properties

__all__ = ("ATS", "AATS", "ATSC", "AATSC", "MATS", "GATS")


class AutocorrelationBase(Descriptor):
    __slots__ = "_prop", "_order"
    explicit_hydrogens = True

    def __str__(self):
        return "{}{}{}".format(
            self.__class__.__name__,
            self._order,
            self._avec.as_argument,
        )

    def description(self):
        return "{} of lag {} weighted by {}".format(
            self._description_name, self._order, self._avec.get_long())

    def parameters(self):
        return self._order, self._prop

    def __init__(self, order=0, prop="m"):
        self._prop = prop
        self._order = order

    @property
    def _avec(self):
        return AtomicProperty(self.explicit_hydrogens, self._prop)

    @property
    def _cavec(self):
        return CAVec(self._prop)

    @property
    def _gmat(self):
        return GMat(self._order)

    @property
    def _gsum(self):
        return GSum(self._order)

    @property
    def _ATS(self):
        return ATS(self._order, self._prop)

    @property
    def _ATSC(self):
        return ATSC(self._order, self._prop)

    @property
    def _AATSC(self):
        return AATSC(self._order, self._prop)

    rtype = float


class AutocorrelationProp(AutocorrelationBase):
    __slots__ = ()

    def parameters(self):
        return (self._prop,)

    def __init__(self, prop):
        self._prop = prop

    rtype = None


class AutocorrelationOrder(AutocorrelationBase):
    __slots__ = ()

    def _prop(self):
        pass

    def parameters(self):
        return (self._order,)

    def __init__(self, order):
        self._order = order

    rtype = None


class CAVec(AutocorrelationProp):
    __slots__ = ()
    _order = 0

    def dependencies(self):
        return {"avec": self._avec}

    def calculate(self, avec):
        return avec - avec.mean()


class GMat(AutocorrelationOrder):
    __slots__ = ()

    def dependencies(self):
        return {"dmat": DistanceMatrix(self.explicit_hydrogens)}

    def calculate(self, dmat):
        return dmat == self._order


class GSum(AutocorrelationOrder):
    __slots__ = ()

    def dependencies(self):
        return {"gmat": GMat(self._order)}

    def calculate(self, gmat):
        s = gmat.sum()

        return s if self._order == 0 else 0.5 * s


MAX_DISTANCE = 8


[docs]class ATS(AutocorrelationBase): r"""Autocorrelation of Topological Structure descriptor. a.k.a. Moreau-Broto autocorrelation descriptor .. math:: {\rm ATS}_0 = \sum^{A}_{i=1} {\boldsymbol w}_i^2 {\rm ATS}_k = \frac{1}{2} \left( {\boldsymbol w}^{\rm T} \cdot {}^k{\boldsymbol B} \cdot {\boldsymbol w} \right) {}^k{\boldsymbol B} = \begin{cases} 1 & (d_{ij} = k) \\ 0 & (d_{ij} \neq k) \end{cases} where :math:`{\boldsymbol w}` is atomic property vector, :math:`d_{ij}` is graph distance(smallest number of bonds between atom i and j). :type order: int :param order: order(:math:`k`) :type property: str, function :param property: :ref:`atomic_properties` :returns: NaN when any properties are NaN """ since = "1.0.0" __slots__ = () _description_name = "moreau-broto autocorrelation" @classmethod def preset(cls, version): return ( cls(d, a) for a in get_properties(valence=True) for d in range(MAX_DISTANCE + 1) ) def dependencies(self): return {"avec": self._avec, "gmat": self._gmat} def calculate(self, avec, gmat): if self._order == 0: return (avec ** 2).sum().astype("float") return 0.5 * avec.dot(gmat).dot(avec)
[docs]class AATS(ATS): r"""averaged ATS descriptor. .. math:: {\rm AATS}_k = \frac{{\rm ATS}_k}{\Delta_k} where :math:`\Delta_k` is number of vertex pairs at order equal to :math:`k`. :Parameters: see :py:class:`ATS` :returns: NaN when * :math:`\Delta_k = 0` * some properties are NaN """ since = "1.0.0" __slots__ = () _description_name = "averaged moreau-broto autocorrelation" def dependencies(self): return {"ATS": self._ATS, "gsum": self._gsum} def calculate(self, ATS, gsum): with self.rethrow_zerodiv(): return ATS / gsum
[docs]class ATSC(AutocorrelationBase): r"""centered ATS descriptor. ATS with :math:`{\boldsymbol w}_{\rm c}` property .. math:: {\boldsymbol w}_{\rm c} = {\boldsymbol w} - \bar{\boldsymbol w} :Parameters: see :py:class:`ATS` :returns: NaN when any properties are NaN """ since = "1.0.0" __slots__ = () _description_name = "centered moreau-broto autocorrelation" @classmethod def preset(cls, version): return ( cls(d, a) for a in get_properties(charge=True, valence=True) for d in range(MAX_DISTANCE + 1) ) def dependencies(self): return {"cavec": self._cavec, "gmat": self._gmat} def calculate(self, cavec, gmat): if self._order == 0: return (cavec ** 2).sum().astype("float") return 0.5 * cavec.dot(gmat).dot(cavec)
[docs]class AATSC(ATSC): r"""averaged ATSC descriptor. .. math:: {\rm AATSC}_k = \frac{{\rm ATSC}_k}{\Delta_k} where :math:`\Delta_k` is number of vertex pairs at order equal to :math:`k`. :Parameters: see :py:class:`ATS` :returns: NaN when * :math:`\Delta_k = 0` * any properties are NaN """ since = "1.0.0" __slots__ = () _description_name = "averaged and centered moreau-broto autocorrelation" def dependencies(self): return {"ATSC": self._ATSC, "gsum": self._gsum} def calculate(self, ATSC, gsum): with self.rethrow_zerodiv(): return ATSC / gsum
[docs]class MATS(AutocorrelationBase): r"""Moran coefficient descriptor. .. math:: {\rm MATS}_k = \frac{ {\rm AATSC}_k }{ \frac{1}{A} \cdot \sum {\boldsymbol w}_{\rm c}^2 } :Parameters: see :py:class:`ATS` :returns: NaN when * some properties are NaN * denominator = 0 """ since = "1.0.0" __slots__ = () _description_name = "moran coefficient" @classmethod def preset(cls, version): return ( cls(d, a) for a in get_properties(charge=True, valence=True) for d in range(1, MAX_DISTANCE + 1) ) def dependencies(self): return { "AATSC": self._AATSC, "avec": self._avec, "cavec": self._cavec, } def calculate(self, avec, AATSC, cavec): with self.rethrow_zerodiv(): return len(avec) * AATSC / (cavec ** 2).sum()
[docs]class GATS(MATS): r"""Geary coefficient descriptor. :Parameters: see :py:class:`ATS` :returns: NaN when * :math:`\Delta_k = 0` * any properties are NaN * denominator = 0 """ since = "1.0.0" __slots__ = () _description_name = "geary coefficient" def dependencies(self): return { "avec": self._avec, "cavec": self._cavec, "gmat": self._gmat, "gsum": self._gsum, } def calculate(self, avec, gmat, gsum, cavec): if len(avec) <= 1: self.fail(ValueError("no bond")) with self.rethrow_zerodiv(): n = (gmat * (avec[:, np.newaxis] - avec) ** 2).sum() / (4 * gsum) d = (cavec ** 2).sum() / (len(avec) - 1) return n / d